Interview, Explained

In-depth breakdowns of tech interviews — section-by-section analysis with diagrams, quotes, and insights.

~64 min
The Cognitive Revolution·

Alex Rives on the data bottleneck behind a world model of life

Alex Rives· Head of Science at Chan Zuckerberg Biohub

Biohub's head of science argues virtual-cell AI is held back less by model design than by what instruments can measure, and lays out a 1.8 billion dollar push to generate the cell data a world model of life would need.

LLMTrainingMultimodalAI Infrastructure
~46 min
Big Technology Podcast·

Sundar Pichai on why AI compute isn't dark fiber

Sundar Pichai· CEO

Alphabet's CEO argues the AI build-out is real demand rather than a bubble, explains why Google spends its scarcest resource, compute, on the frontier before its cloud business, and lays out how it tries to keep recursive self-improvement, the vanishing interface, and its own optimism disciplined.

LLMAgentsAI CompanyAI InfrastructureBusiness Strategy
~40 min
All-In·

Dylan Field on Why Design Is the New Code

Dylan Field· Co-founder and CEO of Figma

Figma's CEO argues that as AI commoditizes code and production, the scarce and defensible layer becomes design, point of view, and the human choice to create rather than consume.

AI CompanyBusiness StrategyAgents
~31 min
TechCrunch Disrupt 2026·

Nader Khalil & Sydney Sykes on What AI Can't Commoditize

Nader Khalil & Sydney Sykes· Director of Developer Tech and Global Head of VC Partnerships, NVIDIA

Two NVIDIA leaders argue that when AI lets anyone build anything, the only durable advantages are the ones it cannot copy: velocity, genuinely hard problems, proprietary and physical data, and the founder's own judgment.

AgentsAI SafetyAI InfrastructureOpen SourceBusiness Strategy
~29 min
TechCrunch Disrupt 2026·

Ben Lamm on running de-extinction like a platform company

Ben Lamm· CEO of Colossal Biosciences

Colossal's CEO reframes de-extinction as the demo for a reusable synthetic-biology platform: AI narrows the genome search, the famous animals fund the research, and the real prize is 'programmable life' across medicine, agriculture, and materials.

AI CompanyBusiness Strategy
~59 min
a16z Podcast·

Jad Naous on why AI solved code but not operations

Jad Naous· CEO

Grepr CEO Jad Naous argues AI conquered coding because code lives in the same distribution it was trained on, while operating real production systems stays hard — so his bet is to hand the AI a deterministic signal that something changed and let it run a bounded debugging playbook instead of asking it to predict the chaos.

AgentsAI InfrastructureBusiness Strategy
~34 min
TechCrunch Disrupt 2026·

Arsalan Tavakoli-Shiraji on why the best tech doesn't win enterprises

Arsalan Tavakoli-Shiraji· Co-founder & SVP of Field Engineering at Databricks

Databricks co-founder Arsalan Tavakoli-Shiraji on why enterprise AI is years behind the valley, and why the winners will own the context, distribution, and domain expertise around the model, not the model itself.

AgentsAI CompanyBusiness StrategyAI InfrastructureOpen Source
~37 min
Big Technology Podcast·

Vijoy Pandey on why every multi-agent system fails silently

Vijoy Pandey· SVP & GM, Outshift

Outshift's Vijoy Pandey says connected agents fail silently: bad assumptions compound until three cognitive failures crater measured accuracy from 98% to 16%, and he argues the same probabilistic shift is remaking computing all the way down to quantum.

AgentsAI SafetyAI InfrastructureOpen Source
~52 min
The TWIML AI Podcast·

Zoe Weil on ranking that moves you, not finds things

Zoe Weil· Co-founder and CEO

Sequen reranks retail products in real time from the signals most systems ignore, such as hover time and scroll speed, to influence behavior in a high-intent moment, judging itself by what people buy rather than what they click.

AI CompanyTrainingInferenceAI InfrastructureBusiness Strategy
~26 min
Bloomberg New Economy Forum·

Gary Marcus on why AI only works where answers get verified

Gary Marcus· Emeritus Professor of Psychology and Neural Science

Gary Marcus argues today's AI is reliable only where answers can be externally verified, so the hype, the sky-high valuations, and the extinction fears all overshoot what the technology can actually do.

AI SafetyLLMReasoningPolicyBusiness Strategy
~51 min
a16z Podcast·

Terry Angelos on how payment credentials turned AI agents into actors

Terry Angelos· Chief Strategy Officer at VGS

Once AI agents got access to payment credentials they jumped from recommending purchases to making them, and that one change is forcing a rebuild of the whole trust stack — vaults, tokens, chargebacks, merchant rules, and who is liable when an agent gets it wrong.

AgentsAI InfrastructureBusiness Strategy
~39 min
No Priors·

Greg Brockman on why new knowledge from AI is now impossible to deny

Greg Brockman· President and co-founder

OpenAI president Greg Brockman argues AI has crossed from giving answers to generating genuinely new knowledge — pointing to roughly 400 resolved open math problems — and says the same shift is about to rewrite the physics of drug discovery and cybersecurity, with the whole project being to keep humans in the driver's seat.

AI SafetyLLMAgentsReasoningAI CompanyPolicy